| Date | Game | Location | TV | Time |
| 12/02/09 | Georgia Tech @ Penn State | University Park, Pa. (Big Ten/ACC Challenge) | | 6:30 p.m. |
| | Illinois @ Wake Forest | Winston, N.C. | | 7:00 p.m.
Gametracker |
| | Boston College @ Iowa | Iowa City, Iowa (Big Ten/ACC Challenge) | | 8:30 p.m.
Gametracker |
| 12/03/09 | Florida State @ Indiana | Bloomington, Ind. (Big Ten/ACC Challenge) | | 7:00 p.m.
Gametracker |
| | Michigan @ Virginia Tech | Blacksburg, Va. (Big Ten/ACC Challenge) | | 7:00 p.m. |
| | Minnesota @ Maryland | College Park, Md. (Big Ten/ACC Challenge) | | 7:00 p.m.
Gametracker |
| | Ohio State @ Duke | Durham, N.C. (Big Ten/ACC Challenge) | | 7:00 p.m. |
| | Purdue @ Virginia | Charlottesville, Va. (Big Ten/ACC Challenge) | | 7:00 p.m. |
| | Wisconsin @ NC State | Raleigh, N.C. (Big Ten/ACC Challenge) | | 7:00 p.m. |
| | Clemson @ Northwestern | Evanston, Ill. (Big Ten/ACC Challenge) | | 8:00 p.m.
Gametracker |
| | North Carolina @ Michigan State | East Lansing, Mich. (Big Ten/ACC Challenge) | | 8:30 p.m.
Gametracker |
| 12/05/09 | Wake Forest @ Georgetown | Washington, D.C. | | 1:00 p.m. |
| | Monmouth @ Boston College | Chestnut Hill, Mass. | | 2:00 p.m.
Gametracker |
| | Nebraska @ Miami | Coral Gables, Fla. | | 2:00 p.m.
Gametracker |
| 12/06/09 | Loyola (Md) @ Maryland | College Park, Md. | | 2:00 p.m.
Gametracker |
| | TCU @ NC State | Raleigh, N.C. | | 2:00 p.m. |
| | USC @ Duke | Durham, N.C. | | 2:00 p.m. |
| | Georgia Tech @ Georgia | Athens, Ga. | | 2:30 p.m. |
| | Charleston Southern @ Clemson | Clemson, S.C. | | 4:00 p.m.
Gametracker |
| | St. John's @ North Carolina | Chapel Hill, N.C. | | 4:30 p.m.
Gametracker |
| | Alcorn State @ Florida State | Tallahassee, Fla. | | 5:00 p.m.
Gametracker |
| | James Madison @ Virginia | Charlottesville, Va. | | TBA |
| | North Carolina Central @ Virginia Tech | Blacksburg, Va. | | TBA |
| 12/08/09 | Mount St. Mary's @ Virginia Tech | Blacksburg, Va. | | 5:30 p.m. |
| | Furman @ Virginia | Charlottesville, Va. | | 7:00 p.m. |
| | Radford @ North Carolina | Chapel Hill, N.C. | | 7:00 p.m.
Gametracker |
| 12/10/09 | Maryland @ Towson | Towson, Md. | | 7:00 p.m. |
| | Michigan @ Boston College | Chestnut Hill, Mass. | | 7:00 p.m.
Gametracker |
| 12/12/09 | Clemson @ UT Chattanooga | Chattanooga, Tenn. | | 7:00 p.m. |
| 12/13/09 | Boston College vs. Baylor | New York, N.Y. (Maggie Dixon Classic) | | 1:00 p.m.
Gametracker |
| | Mississippi Valley State @ Georgia Tech | Atlanta, Ga. | | 2:00 p.m. |
| | NC State @ South Carolina | Columbia, S.C. | | 2:00 p.m.
Gametracker |
| | Gardner-Webb @ North Carolina | Chapel Hill, N.C. | | 3:00 p.m.
Gametracker |
| 12/14/09 | North Florida @ Wake Forest | Winston-Salem, N.C. | | 11:30 a.m.
Gametracker |
| 12/15/09 | USC Upstate @ Clemson | Clemson, S.C. | | 7:00 p.m.
Gametracker |
| | Duke @ Stanford | Stanford, Calif. | | 10:00 p.m.
Gametracker |
| 12/16/09 | Oregon @ Georgia Tech | Atlanta, Ga. | | 6:00 p.m. |
| | Florida State @ UCF | Orlando, Fla. | | 7:00 p.m.
Gametracker |
| 12/17/09 | Wake Forest @ South Carolina | Columbia, S.C. | | 7:00 p.m.
Gametracker |
| 12/18/09 | Georgia Tech @ Kennesaw State | Kennesaw, Ga. | | 7:00 p.m. |
| | James Madison @ Duke | Durham, N.C. | | 7:00 p.m. |
| 12/19/09 | Clemson @ Ohio | Athens, Ohio | | 12:00 p.m.
Gametracker |
| | Miami @ Binghamton | Binghamton, N.Y. | | 2:00 p.m. |
| | Wofford @ Wake Forest | Winston-Salem, N.C. | | 2:00 p.m.
Gametracker |
| | Florida State vs. Texas-San Antonio | Las Vegas, Nev. (Duel in the Desert) | | 3:00 p.m. |
| | Virginia Tech vs. UAB | Queens, N.Y. (St. John's Tournament) | | 3:00 p.m. |
| | Winthrop @ NC State | Raleigh, N.C. | | 5:00 p.m. |
| 12/20/09 | Arizona @ Georgia Tech | Atlanta, Ga. | | 1:00 p.m. |
| | Wright State @ Boston College | Chestnut Hill, Mass. | | 1:00 p.m.
Gametracker |
| | Maryland @ American | Washington, D.C. | | 2:00 p.m. |
| | Virginia @ Georgia | Athens, Ga. | | 2:30 p.m. |
| | North Carolina vs. South Carolina | Myrtle Beach, S.C. | | 3:00 p.m. |
| | Florida State vs. TBD | Las Vegas, Nev. (Duel in the Desert) | | TBA |
| | Virginia Tech vs. UTA/St. John's | Queens, N.Y. (St. John's Tournament) | | TBA |
| 12/21/09 | Duke @ Maine | Orono, Maine | | 7:00 p.m.
Gametracker |
| | Miami @ Cornell | Ithaca, N.Y. | | 7:00 p.m. |
| | Wofford @ Clemson | Clemson, S.C. | | 7:00 p.m.
Gametracker |
| | Florida State vs. TBD | Las Vegas, Nev. (Duel in the Desert) | | TBA |
| 12/22/09 | Georgia Tech @ Georgia State | Atlanta, Ga. | | 12:00 p.m. |
| | NC State @ Georgetown | Washington, D.C. | | 7:00 p.m. |
| 12/27/09 | Stony Brook @ Maryland | College Park, Md. (Terrapin Classic) | | 4:30 p.m. |
| 12/28/09 | Connecticut @ Florida State | Tallahassee, Fla. | | 7:00 p.m. |
| | Georgia @ Clemson | Clemson, S.C. | | 7:00 p.m. |
| | Georgia Tech vs. Hampton | Miami, Fla. (FIU Tournament) | | 7:00 p.m. |
| | North Carolina Central @ Duke | Durham, N.C. | | 7:00 p.m. |
| | Quinnipiac @ Miami | Coral Gables, Fla. (UM Holiday Tournament) | | 7:00 p.m. |
| | Seton Hall @ NC State | Raleigh, N.C. | | 7:00 p.m. |
| | Cal @ Boston College | San Diego, Calif. (Surf 'N Slam) | | 8:00 p.m. |
| | Wake Forest @ San Diego State | San Diego, Calif. (SDSU Tournament) | | 8:00 p.m. |
| | Samford @ Virginia | Charlottesville, Va. (Cavalier Classic) | | TBA |
| 12/29/09 | Kennesaw State @ North Carolina | Chapel Hill, N.C. | | 2:00 p.m. |
| | NJIT @ Virginia Tech | Blacksburg, Va. (Hilton Garden Classic) | | 7:00 p.m. |
| | UNC-Wilmington @ Maryland | College Park, Md. (Terrapin Classic) | | 7:00 p.m. |
| | Georgia Tech vs. Bryant/FIU | Miami, Fla. (FIU Tournament) | | TBA |
| | Liberty/Cornell @ Virginia | Charlottesville, Va. (Cavalier Classic) | | TBA |
| | Texas/Central Michigan @ Miami | Coral Gables, Fla. (UM Tournament) | | TBA |
| | Wake Forest vs Auburn/Valpo | San Diego, Calif. (SDSU Tournament) | | TBA |
| 12/30/09 | Charlotte/Central Conn. State @ Virginia Tech | Blacksburg, Va. (Hilton Garden Classic) | | 7:00 p.m. |
| | Georgetown @ Clemson | Clemson, S.C. | | 7:00 p.m. |
| | Western Carolina @ Florida State | Tallahassee, Fla. | | 7:00 p.m. |
| | NC State @ USC | Los Angeles, Calif. | | 9:00 p.m. |
| | Boston College vs. San Diego/Nevada | San Diego, Calif. (Surf 'N Slam) | | TBA |
| 12/31/09 | Duke @ Temple | Philadelphia, Pa. | | 2:00 p.m. |
| | East Tennessee State @ North Carolina | Chapel Hill, N.C. | | 2:00 p.m. |
| | UNF @ Miami | Coral Gables, Fla. | | 2:00 p.m. |
