| Date | Opponent | Location | TV | Info/Time/Recap |
| 09/01/12 | North Carolina 62, Elon 0 | Chapel Hill, N.C. | ACC Network (XM 191 :: SIRIUS 136) | Recap | Gametracker | Highlights |
| | Maryland 7, William & Mary 6 | College Park, Md. | ESPN3 (SIRIUS 134) | Recap | Gametracker | Highlights |
| | Virginia 43, Richmond 19 | Charlottesville, Va. | RSN (XM 190 :: SIRIUS 92) | Recap | Gametracker | Highlights |
| | Miami 41, Boston College 32 | Chestnut Hill, Mass. | ABC/ESPN2 (XM 91 :: SIRIUS 91) | Recap | Gametracker | Highlights | ACC Day |
| | Florida State 69, Murray State 3 | Tallahassee, Fla. | ESPN3 (XM 1920 :: SIRIUS 135) | Recap | Gametracker | Highlights |
| | Wake Forest 20, Liberty 17 | Winston-Salem, N.C. | ESPN3 (XM 190 :: SIRIUS 92) | Recap | Gametracker | Highlights |
| | Clemson 26, Auburn 19 | Atlanta, Ga.
(Chick-fil-A Kickoff) | ESPN (XM 198 :: SIRIUS 94) | Recap | Highlights |
| | Duke 46, FIU 26 | Durham, N.C. | ESPN3 (SIRIUS 134) | Recap | Gametracker | Highlights |
| 09/03/12 | Virginia Tech 20, Georgia Tech 17 ( OT ) | Blacksburg, Va. | ESPN (XM 91 :: SIRIUS 91) | Recap | Gametracker | Highlights | ACC Day |
| 09/08/12 | Kansas State 52, Miami 13 | Manhattan, Kansas | FX (XM 195 :: SIRIUS 136) | Recap | Gametracker | Highlights |
| | Maryland 36, Temple 27 | Philadelphia, Pa. | ESPNU (XM 192 :: SIRIUS 134) | Recap | Gametracker | Highlights |
| | NC State 10, Connecticut 7 | East Hartford, Conn. | Big East Network/ESPN3 (XM 193 :: SIRIUS 137) | Recap | Gametracker | Highlights |
| | Virginia 17, Penn State 16 | Charlottesville, Va. | ABC (XM 91 :: SIRIUS 91) | Recap | Gametracker | Highlights |
| | Clemson 52, Ball State 27 | Clemson, S.C. | ACC Network (XM 190 :: SIRIUS 92) | Recap | Gametracker | Highlights |
| | Boston College 34, Maine 3 | Chestnut Hill, Mass. | ESPN3 (SIRIUS 128) | Recap | Gametracker |
| | Virginia Tech 42, Austin Peay 7 | Blacksburg, Va. | ESPN3 (XM 191 :: SIRIUS 93) | Recap | Gametracker | Highlights |
| | Wake Forest 28, North Carolina 27 | Winston-Salem, N.C. | RSN (XM 197 :: SIRIUS 132) | Recap | Gametracker | Highlights | ACC Day |
| | Florida State 55, Savannah State 0 | Tallahassee, Fla. | ESPN3 (XM 191 :: SIRIUS 93) | Recap | Gametracker | ACCDN Highlights |
| | Georgia Tech 59, Presbyterian 3 | Atlanta, Ga. | ESPN3 (SIRIUS 106) | Recap | Gametracker | Highlights |
| | Stanford 50, Duke 13 | Stanford, Calif. | PAC-12 Network Bay Area (SIRIUS 128) | Recap | Gametracker |
| 09/15/12 | Florida State 52, Wake Forest 0 | Tallahassee, Fla. | ESPN (XM 190 :: SIRIUS 93) | Recap | Gametracker | Higlights | Military Appreciation Day | ACC Day |
| | Miami 38, Bethune-Cookman University 10 | Miami Gardens, Fla. | ESPN3 (XM 192 :: SIRIUS 136) | Recap | Gametracker | Highlights |
| | Pitt 35, Virginia Tech 17 | Pittsburgh, Pa. | ESPNU (XM 85 :: SIRIUS 85) | Recap | Gametracker | Highlights |
| | UConn 24, Maryland 21 | College Park, Md. | ACC Network (XM 191 :: SIRIUS 132) | Recap | Gametracker | Highlights |
| | Clemson 41, Furman 7 | Clemson, S.C. | RSN (XM 198 :: SIRIUS 80) | Recap | Gametracker | Highlights |
| | Georgia Tech 56, Virginia 20 | Atlanta, Ga. | ESPNU (XM 190 :: SIRIUS 93) | Recap | Gametracker | Highlights | ACC Day |
| | Louisville 39, North Carolina 34 | Louisville, Ky. | ABC/ESPN2 (XM 85 :: SIRIUS 85) | Recap | Gametracker | Highlights |
| | Northwestern 22, Boston College 13 | Evanston, Ill. | Big Ten Network (SIRIUS 112) | Recap | Gametracker | Highlights |
| | NC State 31, South Alabama 7 | Raleigh, N.C. | ESPN3 (SIRIUS 135) | Recap | Gametracker | Highlights |
| | Duke 54, NCCU 17 | Durham, N.C. | ESPN3 (SIRIUS 134) | Recap | Gametracker | Highlights |
| 09/22/12 | TCU 27, Virginia 7 | Fort Worth, Texas | ESPN (XM 91 :: SIRIUS 91) | Recap | Gametracker | Highlights |
| | Virginia Tech 37, Bowling Green 0 | Blacksburg, Va. | ESPNU (XM 191 :: SIRIUS 94) | Recap | Gametracker | Highlights | Military Appreciation Day |
| | West Virginia 31, Maryland 21 | Morgantown, W. Va. | FX (XM 85 :: SIRIUS 85) | Recap | Gametracker | Highlights |
| | Wake Forest 49, Army 37 | Winston-Salem, N.C. | ACC Network (XM 190 :: SIRIUS 92) | Recap | Gametracker | Highlights | Military Appreciation Day |
| | Miami 42, Georgia Tech 36 ( OT ) | Atlanta, Ga. | RSN (XM 192 :: 137) | Recap | Gametracker | Highlights |
| | North Carolina 27, East Carolina 6 | Chapel Hill, N.C. | ESPNU (XM 191 :: SIRIUS 94) | Recap | Gametracker | Highlights |
| | Duke 38, Memphis 14 | Durham, N.C. | ESPN3 (XM 190 :: SIRIUS 132) | Recap | Gametracker | Highlights |
| | NC State 52, The Citadel 14 | Raleigh, N.C. | ESPN3 (SIRIUS 125) | Recap | Gametracker | Highlights | Military Appreciation Day |
| | Florida State 49, Clemson 37 | Tallahassee, Fla. | ABC (XM 86 :: SIRIUS 86) | Recap | Gametracker | Highlights |
| 09/29/12 | Miami 44, NC State 37 | Miami, Fla. | ESPNU (XM 191 :: SIRIUS 136) | Recap | Gametracker | Highlights | ACC Day |
| | Middle Tennessee 49, Georgia Tech 28 | Atlanta, Ga. | RSN (XM 190 :: SIRIUS 112) | Recap | Gametracker | Highlights | Watch Live Online! |
| | Duke 34, Wake Forest 27 | Winston-Salem, N.C. | ACC Network (XM 192 :: SIRIUS 135) | Recap | Gametracker | Highlights |
| | Cincinnati 27, Virginia Tech 24 | FedEx Field, Landover, Md. | ESPNU (XM 190 :: SIRIUS 112) | Recap | Gametracker | Highlights |
| | Clemson 45, Boston College 31 | Chestnut Hill, Mass. | ESPN2 (XM 194 :: SIRIUS 132) | Recap | Gametracker | Highlights |
| | Louisiana Tech 44, Virginia 38 | Charlottesville, Va. | ESPN3 (XM 199 :: SIRIUS 113) | Recap | Gametracker | Highlights |
| | North Carolina 66, Idaho 0 | Chapel Hill, N.C. | RSN (XM 196 :: SIRIUS 138) | Recap | Gametracker | Highlights | Military Appreciation Day |
| | Florida State 30, USF 17 | Tampa, Fla. | ESPN (XM 191 :: SIRIUS 136) | Recap | Gametracker | Highlights |
