| Date | Opponent | Location | Outcome/Time |
| 10/02/09 | Florida Atlantic , Florida State | Tallahassee, Fla. | 3:00 p.m.
Recap | W: FSU-175; FAU-100
M: FSU-174; FAU-101 |
| 10/03/09 | FIU , Florida State | Tallahassee, Fla. | 11:00 a.m.
Recap | W: FSU-137; FIU-89 |
| 10/03/09 | Clemson @ Davidson | Davidson, N.C. | 1:00 p.m.
Recap | W: Clemson-183; Davidson-92
M: Clemson-177; Davidson-123 |
| 10/03/09 | Georgia Southern, FAU, Florida Gulf Coast, Alabama @ Georgia Tech | Atlanta, Ga. | 1:00 p.m.
Recap | W: Georgia Tech: 3-1
M: Georgia Tech: 1-1 |
| 10/08/09 | North Carolina @ East Carolina | Greenville, N.C. | 6:00 p.m.
Recap | M: UNC 187, ECU 105; W: UNC 183, ECU 105 |
| 10/09/09 | Boston College @ Army | Chapel Hill, N.C. | 4:00 p.m.
Recap | W: Boston College: 2-1 M: Boston College: 1-1. |
| 10/10/09 | Clemson, Miami (W), Western Kentucky @ Georgia Tech | Atlanta, Ga. | 11:00 a.m.
Recap | W: Clemson: 3-0 M: Clemson: 1-1; W: Miami: 0-3; W: Georgia Tech: 1-1-1 M: Georgia Tech: 2-0. |
| 10/16/09 | Boston College @ Harvard (Women Only) | Boston, Mass. | 4:00 p.m. |
| 10/16/09 | TBD @ Boston College (Men Only) | Chestnut Hill, Mass. | 8:00 p.m. |
| 10/17/09 | South Carolina, Virginia Tech @ North Carolina | Chapel Hill, N.C. | 12:00 p.m.
Recap | W: North Carolina: 2-0 M: North Carolina: 2-0; W: Virginia Tech: 1-1 M: Virginia Tech: 1-1. |
| 10/17/09 | Florida State, Miami @ Florida Gulf Coast (W) | Ft. Myers, Fla. | 1:00 p.m.
Recap | W: Florida State: 2-0; W: Miami: 0-2. |
| 10/17/09 | UNC-Wilmington @ Duke | Durham, N.C. | 2:00 p.m.
Recap | M: Duke 163, UNCW 137; W: Duke 175, UNCW 120. |
| 10/18/09 | Canisius @ Boston College | Chestnut Hill, Mass. | 1:00 p.m. |
| 10/21/09 | Virginia @ Virginia Tech | Blacksburg, Va. | 5:00 p.m.
Recap | M: UVa 177, VT 123; W: UNC 180, VT 120 |
| 10/23/09 | Georgetown , Maryland | College Park, Md. | [@]
Recap | M: MD-146.5, JHU 91.5; W: MD-187, JHU-67 |
| 10/23/09 | North Carolina @ Georgia | Athens, Ga. | 3:00 p.m.
Recap | M: UNC-156, UGA-144; W: UGA-160, UNC 126 |
| 10/23/09 | Florida @ Georgia Tech | Atlanta, Ga. | 6:00 p.m.
Recap | UF: 161, GS: 123 |
| 10/23/09 | Florida A&M @ Florida State | Tallahassee, Fla. | TBA
M: FSU 79, FAMU 58; W: FSU-76, FAMU 47 |
| 10/23/09 | Florida State @ Southern Methodist Classic (Women) | Dallas, Texas | All Day
Recap | W: 5th-FSU 257. |
| 10/24/09 | Duke, NC State @ Maryland | College Park, Md. | 1:00 p.m.
Recap | W: Maryland: 2-0 M: Maryland: 0-2; W: NC State: 1-1 M: NC State: 2-0; W: Duke: 0-2 M: Duke: 1-1. |
| 10/30/09 | NCAC Mile Meet (Hosted by North Carolina) | Chapel Hill, N.C. | 2:00 p.m.
Recap |
| 10/30/09 | South Carolina , Clemson | Clemson, S.C. | [@]
Recap | W: Clemson 155, USC 145; M: Clemson 160, USC 140 |
| 10/30/09 | Georgia Tech, Houston @ Duke | Durham, N.C. | 6:00 p.m.
Recap | W: Duke 178, GT 120; GT 179, UH 119; M: Duke 171, GT 128.5 |
| 10/31/09 | Georgia Tech @ North Carolina | Chapel Hill, N.C. | 11:00 a.m.
Recap | W:UNC 165, GT 128; M: UNC 165.5, GT 119.5 |
| 10/31/09 | Richmond, Campbell @ NC State | Chapel Hill, N.C. | 11:00 a.m.
Recap | W: NC State: 2-0 |
| 10/31/09 | Penn State @ Virginia Tech | Blacksburg, Va. | 12:00 p.m.
Recap | W: VT 160, PSU 140; M: VT 184, PSU 116 |
| 11/01/09 | Boston College @ Bryant University | Smithfield, R.I. | 1:00 p.m. |
| 11/06/09 | Kentucky @ Virginia Tech | Blacksburg, Va. | 3:00 p.m.
Recap | W: VT 176, UK 122; M: VT 161.5-136.5 |
| 11/06/09 | Maryland @ North Carolina | Chapel Hill, N.C. | 3:00 p.m.
Recap | W: UNC 166, UM 117; M: UNC 171, UM 98 |
| 11/07/09 | LSU @ Florida State | Tallahassee, Fla. | 11:00 a.m.
Recap | M: FSU 146, LSU 144; W: FSU 162, LSU 138 |
| 11/07/09 | Colgate @ Boston College | Charlottesville, Va. | 12:00 p.m. |
| 11/07/09 | Miami & Duke @ Virginia Tech | Blacksburg, Va. | 12:00 p.m.
Recap | M: VT 180, DU 112; W: VT 174, DU 126; VT: 208, UM 86; DU 184, UM: 104 |
| 11/07/09 | NC State @ Davidson | Davidson, N.C. | 1:00 p.m.
Recap | M: NCSU 167, DC 100; W: NCSU 157, DC 129 |
| 11/14/09 | Towson, UMBC @ Maryland | College Park, Md. | 1:00 p.m.
Recap |
| 11/19/09 | Duke, North Carolina @ Gamecock Invitational (Hosted by South Carolina) | Columbia, S.C. | All Day |
| 11/19/09 | Terrapin Invitational (Hosted by Maryland) | College Park, Md. | All Day |
| 11/19/09 | Virginia Tech @ Volunteer Invitational (Hosted by Tennessee) | Knoxville, Tenn. | All Day |
| 11/20/09 | Boston College @ Terrier Invitational (Hosted by Boston University) | Boston, Mass. | All Day |
| 11/20/09 | Clemson, Florida State, NC State @ Georgia Tech Invitational | Atlanta, Ga. | All Day |
| 11/20/09 | Duke, North Carolina @ Gamecock Invitational (Hosted by South Carolina) | Columbia, S.C. | All Day |
| 11/20/09 | Terrapin Invitational (Hosted by Maryland) | College Park, Md. | All Day |
| 11/20/09 | Virginia Tech @ Volunteer Invitational (Hosted by Tennessee) | Knoxville, Tenn. | All Day |
| 11/21/09 | Boston College @ Terrier Invitational (Hosted by Boston University) | Boston, Mass. | All Day |
| 11/21/09 | Clemson, Florida State, NC State @ Georgia Tech Invitational | Atlanta, Ga. | All Day |
| 11/21/09 | Duke, North Carolina @ Gamecock Invitational (Hosted by South Carolina) | Columbia, S.C. | All Day |
| 11/21/09 | Terrapin Invitational (Hosted by Maryland) | College Park, Md. | All Day |
| 11/21/09 | Virginia Tech @ Volunteer Invitational (Hosted by Tennessee) | Knoxville, Tenn. | All Day |
| 11/22/09 | Boston College @ Terrier Invitational (Hosted by Boston University) | Boston, Mass. | All Day |
| 11/22/09 | Clemson, Florida State, NC State @ Georgia Tech Invitational | Atlanta, Ga. | All Day |
| 11/24/09 | Florida State @ Florida | Gainesville, Fla. | 5:00 p.m. |
| 12/03/09 | North Carolina @ USA Swimming Short Course National Championships | Federal Way, Wash. | All Day |
| 12/04/09 | Duke, Miami, NC State @ Ohio State Invitational | Columbus, Ohio | All Day |
| 12/04/09 | North Carolina @ USA Swimming Short Course National Championships | Federal Way, Wash. | All Day |
| 12/05/09 | Boston College @ Williams College & Fordham | Bronx, N.Y. | 12:00 p.m. |
| 12/05/09 | Duke, Miami, NC State @ Ohio State Invitational | Columbus, Ohio | All Day |
| 12/05/09 | North Carolina @ USA Swimming Short Course National Championships | Federal Way, Wash. | All Day |
| 12/06/09 | Duke, Miami, NC State @ Ohio State Invitational | Columbus, Ohio | All Day |
| 12/17/09 | Georgia Tech @ Bama Diving Invite | Tuscaloosa, Ala. | All Day |
| 12/18/09 | Clemson @ Florida Atlantic | Boca Raton, Fla. | 8:00 a.m. |
| 12/18/09 | Georgia Tech @ Bama Diving Invite | Tuscaloosa, Ala. | All Day |
| 12/19/09 | Georgia Tech @ Bama Diving Invite | Tuscaloosa, Ala. | All Day |
| 01/02/10 | Duke @ Orange Bowl Classic | Key Largo, Fla. | 10:00 a.m. |
| 01/02/10 | Maryland @ Miami | Coral Gables, Fla. | 11:00 a.m. |
| 01/03/10 | Clemson @ Georgia Diving Invitational | Athens, Ga. | All Day |
| 01/04/10 | Clemson @ Georgia Diving Invitational | Athens, Ga. | All Day |
| 01/05/10 | Clemson @ Georgia Diving Invitational | Athens, Ga. | All Day |
| 01/05/10 | Kenyon (Ohio) @ North Carolina | Sarasota, Fla. | TBA |
| 01/08/10 | Illinois, Nebraska @ Miami | Coral Gables, Fla. | 11:00 a.m. |
| 01/09/10 | Clemson @ North Carolina | Chapel Hill, N.C. | 11:00 a.m. |
| 01/09/10 | North Carolina, UNC Wilmington @ Florida State | Tallahassee, Fla. | 11:00 a.m. |
| 01/09/10 | Navy @ Maryland | College Park, Md. | 1:00 p.m. |
| 01/15/10 | Maryland @ Pittsburgh | Pittsbugh, Pa. | 5:00 p.m. |
| 01/16/10 | Central Connecticut State @ Miami | Coral Gables, Fla. | 11:00 a.m. |
| 01/16/10 | Florida State @ Clemson | Clemson, S.C. | 11:00 a.m. |
| 01/16/10 | Maryland @ Pittsburgh | Pittsbugh, Pa. | 11:00 a.m. |
| 01/16/10 | NC State @ Georgia Tech | Atlanta, Ga. | 11:00 a.m. |
| 01/16/10 | Davidson @ Virginia Tech | Clemson, S.C. | 1:00 p.m. |
| 01/16/10 | Duke @ South Carolina | Columbia, S.C. | 2:00 p.m. |
| 01/20/10 | East Carolina @ NC State | Raleigh, N.C. | 5:00 p.m. |
| 01/22/10 | Massachusetts @ Boston College | Chestnut Hill, Mass. | 4:00 p.m. |
| 01/22/10 | Miami @ Florida Atlantic | Boca Raton, Fla. | 5:00 p.m. |
| 01/22/10 | Virginia @ Duke | Durham, N.C. | 5:00 p.m. |
| 01/23/10 | Clemson @ NC State | Raleigh, N.C. | 11:00 a.m. |
| 01/23/10 | Florida State, Virginia Tech @ Georgia Tech | Atlanta, Ga. | 12:00 p.m. |
| 01/23/10 | Virginia @ North Carolina | Chapel Hill, N.C. | 12:00 p.m. |
| 01/23/10 | West Virginia @ Maryland | Chestnut Hill, Mass. | 1:00 p.m. |
| 01/23/10 | Brandeis @ Boston College | Atlanta, Ga. | 6:30 p.m. |
| 01/24/10 | North Carolina @ Duke | Durham, N.C. | 1:00 p.m. |
| 01/24/10 | Tufts University @ Boston College (Men Only) | Chestnut Hill, Mass. | 1:00 p.m. |
| 01/29/10 | Boston College @ Dartmouth & Maine | Orono, Maine | All Day |
| 01/30/10 | Emory @ Georgia Tech | Atlanta, Ga. | 12:00 p.m. |
| 01/30/10 | Virginia Tech @ West Virginia | Morgantown, W.Va. | 12:00 p.m. |
| 01/30/10 | Duke @ Clemson | Clemson, S.C. | 1:00 p.m. |
| 01/30/10 | Pittsburgh @ Virginia | Charlottesville, Va. | 1:00 p.m. |
| 01/30/10 | Boston College @ Maine | Orono, Maine | All Day |
| 02/01/10 | Miami @ USA Diving Winter Nationals Qualifying | TBD | All Day |
| 02/02/10 | Boston College @ Boston University (Men Only) | Boston, Mass. | 6:00 p.m. |
| 02/02/10 | Boston University @ Boston College (Women Only) | Chestnut Hill, Mass. | 6:00 p.m. |
| 02/02/10 | Miami @ USA Diving Winter Nationals Qualifying | TBD | All Day |
| 02/04/10 | Holy Cross @ Boston College | Chestnut Hill, Mass. | 6:00 p.m. |
| 02/04/10 | Florida State Winter Invitational (Hosted by Florida State) | Tallahassee, Fla. | All Day |
| 02/04/10 | Miami @ USA Diving Winter Nationals Championships | TBD | All Day |
| 02/05/10 | NC State @ North Carolina | Chapel Hill, N.C. | 6:00 p.m. |
| 02/05/10 | Florida State Winter Invitational (Hosted by Florida State) | Tallahassee, Fla. | All Day |
| 02/05/10 | Miami @ USA Diving Winter Nationals Championship | TBD | All Day |
| 02/06/10 | Georgetown @ Maryland | College Park, Md. | 1:00 p.m. |
| 02/06/10 | Florida State Winter Invitational (Hosted by Florida State) | Tallahassee, Fla. | All Day |
| 02/06/10 | Miami @ USA Diving Winter Nationals Championship | TBD | All Day |
| 02/06/10 | New England Invitational (Hosted by Boston College) | College Park, Md. | All Day |
| 02/06/10 | Triangle College Cup (Hosted by North Carolina) | Chapel Hill, N.C. | All Day |
| 02/07/10 | Miami @ USA Diving Winter Nationals Championship | TBD | All Day |
| 02/07/10 | Triangle College Cup (Hosted by North Carolina) | Chapel Hill, N.C. | All Day |
| 02/08/10 | Miami @ USA Diving Winter Nationals Championship | TBD | All Day |
| 02/11/10 | Miami @ All-Star Diving Invitational | Orlando, Fla. | All Day |
| 02/12/10 | Miami @ All-Star Diving Invitational | Orlando, Fla. | All Day |
| 02/13/10 | Miami @ All-Star Diving Invitational | Orlando, Fla. | All Day |
| 02/14/10 | Miami @ All-Star Diving Invitational | Orlando, Fla. | All Day |
| 02/17/10 | ACC Swimming & Diving Championships | Chapel Hill, N.C. & Durham, N.C. | All Day |
| 02/18/10 | ACC Swimming & Diving Championships | Chapel Hill, N.C. & Durham, N.C. | All Day |
| 02/19/10 | ACC Swimming & Diving Championships | Chapel Hill, N.C. & Durham, N.C. | All Day |
| 02/20/10 | ACC Swimming & Diving Championships | Chapel Hill, N.C. & Durham, N.C. | All Day |
| 02/24/10 | ACC Swimming & Diving Championships | Chapel Hill, N.C. & Durham, N.C. | All Day |
| 02/25/10 | ACC Swimming & Diving Championships | Chapel Hill, N.C. & Durham, N.C. | All Day |
| 02/26/10 | ACC Swimming & Diving Championships | Chapel Hill, N.C. & Durham, N.C. | All Day |
| 02/27/10 | ACC Swimming & Diving Championships | Chapel Hill, N.C. & Durham, N.C. | All Day |
| 02/27/10 | Boston College @ ECAC Championship (Hosted by Pittsburgh) | Pittsburgh, Pa. | All Day |
| 02/28/10 | Boston College @ ECAC Championship (Hosted by Pittsburgh) | Pittsburgh, Pa. | All Day |
| 03/05/10 | Florida State @ Auburn Invitational (Men Only) | Auburn, Ala. | All Day |
| 03/05/10 | Virginia Tech Swimming Invitational | Christianburg, Va. | All Day |
| 03/06/10 | Florida State @ Auburn Invitational (Men Only) | Auburn, Ala. | All Day |
| 03/06/10 | Virginia Tech Swimming Invitational | Christianburg, Va. | All Day |
